HPC Capabilities
- Streamlined Job Submission workflow
- SLURM HPC cluster management
- NONMEM and PsN integration
- Budget monitoring and reporting
- Governance policy enforcement
A global pharmaceutical leader faced critical bottlenecks in their drug discovery pipeline.
Drug discovery process & clinical product designs were delayed due to dependency on infrastructure requirement to run simulations in traditional VM environments.
Researcher productivity was constrained by infrastructure that lacked support for running parallel simulations and analysis workflows.
Absence of a scalable platform to serve multiple research users who needed to run multiple simulations in parallel simultaneously.
End-to-end deployment of a production-ready AWS HPC environment optimized for running PK/PD workloads using NONMEM.
Implemented an AWS ParallelCluster based HPC environment directly within the customer’s AWS account for full data control and enterprise security.
Configured SLURM HPC cluster with optimized queue and QOS setup adhering to AWS Well Architected practices.
Installed and validated NONMEM, PsN, and FinchStudio on the AWS HPC stack, ensuring seamless execution of bootstrap, estimation, and simulation workloads.
Onboarded platform admins and HPC users with comprehensive self- service capabilities including job submission, monitoring, and governance.
The AWS-native HPC implementation delivered exceptional improvements across all performance metrics.
Submit NONMEM jobs, run parallel simulations, and monitor logs and performance in real time via the HPC workflow environment.
Track compute spend, configure usage alerts, and optimize cost efficiency across research studies.
Generate detailed simulation reports and resource utilization insights for scientific and operational teams.
Implement workload governance, enforce HPC usage policies, and maintain compliance across the cluster.
NONMEM & PsN
AWS EC2
Amazon S3
SLURM Scheduler
FSx for Lustre
RDS
FinchStudio Integration
AWS Parallel Cluster
Learn how Apollo Tyres leveraged Tachyon to scale engineering simulations & drive innovation